Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis.

Rheumatoid arthritis (RA) is now clearly a true autoimmune disease with accumulating evidence of pathogenic disease-specific autoimmunity to citrullinated proteins. Citrullination, also termed deimination, is a modification of arginine side chains catalyzed by peptidylarginine deiminase (PAD) enzyme...

詳細記述

書誌詳細
主要な著者: Wegner, N, Lundberg, K, Kinloch, A, Fisher, B, Malmström, V, Feldmann, M, Venables, P
フォーマット: Journal article
言語:English
出版事項: 2010