Mechanical modulation of receptor-ligand interactions at cell-cell interfaces.

Cell surface receptors have been extensively studied because they initiate and regulate signal transduction cascades leading to a variety of functional cellular outcomes. An important class of immune receptors (e.g., T-cell antigen receptors) whose ligands are anchored to the surfaces of other cells...

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Bibliographic Details
Main Authors: Allard, J, Dushek, O, Coombs, D, Van Der Merwe, P
Format: Journal article
Language:English
Published: 2012