Targeted editing of the pp38 gene in Marek’s disease virus-transformed cell lines using CRISPR/Cas9 system

Marek’s disease virus (MDV), a lymphotropic α-herpesvirus associated with T-cell lymphomas in chickens, is an excellent model for herpesvirus biology and virus-induced oncogenesis. Marek’s disease (MD) is also one of the cancers against which a vaccine was first used. In the lymphomas and lymphoblas...

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Bibliographic Details
Main Authors: Zhang, Y, Luo, J, Tang, N, Teng, M, Reddy, VRAP, Moffat, K, Shen, Z, Nair, V, Yao, Y
Format: Journal article
Language:English
Published: MDPI 2019