A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in vascular resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice
<strong>Background and purpose:</strong> The cofactor tetrahydrobiopterin (BH4) is a critical regulator of endothelial NOS (eNOS) function, eNOS-derived NO and reactive oxygen species (ROS) signalling in vascular physiology. To determine the physiological requirement for de-novo endothel...
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Published: |
John Wiley & Sons Ltd
2017
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