A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in vascular resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice

A key role for tetrahydrobiopterin-dependent endothelial NOS regulation in vascular resistance arteries: studies in endothelial cell tetrahydrobiopterin-deficient mice

<strong>Background and purpose:</strong> The cofactor tetrahydrobiopterin (BH4) is a critical regulator of endothelial NOS (eNOS) function, eNOS-derived NO and reactive oxygen species (ROS) signalling in vascular physiology. To determine the physiological requirement for de-novo endothel...

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Bibliographic Details
Main Authors:	Chuaiphichai, S, Crabtree, M, McNeill, E, Hale, A, Trelfa, L, Channon, K, Douglas, G
Format:	Journal article
Published:	John Wiley & Sons Ltd 2017

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