The protective role of MC1R in chromosome stability and centromeric integrity in melanocytes

The protective role of MC1R in chromosome stability and centromeric integrity in melanocytes

Variants in the melanocortin-1 receptor (MC1R) gene, encoding a trimeric G-protein-coupled receptor and activated by α-melanocyte-stimulating hormone (α-MSH), are frequently associated with red or blonde hair, fair skin, freckling, and skin sensitivity to ultraviolet (UV) light. Several red hair col...

Bibliografski detalji
Glavni autori:	Li, X, Mao, W, Chen, J, Goding, C, Et al.
Format:	Journal article
Jezik:	English
Izdano:	Springer Nature 2021

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od: Cooper, K, i dr.
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Re-replication of a centromere induces chromosomal instability and aneuploidy.
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