Preclinical safety studies of enadenotucirev, a chimeric group B human-specific oncolytic adenovirus

Enadenotucirev is an oncolytic group B adenovirus identified by a process of bio-selection for the ability to selectively propagate in and rapidly kill carcinoma cells. It is resistant to inactivation by human blood components, potentially enabling intravenous dosing in patients with metastatic canc...

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Bibliographic Details
Main Authors: Illingworth, S, Di, Y, Bauzon, M, Lei, J, Duffy, M, Alvis, S, Champion, B, Lieber, A, Hermiston, T, Seymour, L, Beadle, J, Fisher, K
Format: Journal article
Language:English
Published: Elsevier 2017