Preclinical safety studies of enadenotucirev, a chimeric group B human-specific oncolytic adenovirus

Enadenotucirev is an oncolytic group B adenovirus identified by a process of bio-selection for the ability to selectively propagate in and rapidly kill carcinoma cells. It is resistant to inactivation by human blood components, potentially enabling intravenous dosing in patients with metastatic canc...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Illingworth, S, Di, Y, Bauzon, M, Lei, J, Duffy, M, Alvis, S, Champion, B, Lieber, A, Hermiston, T, Seymour, L, Beadle, J, Fisher, K
Format: Journal article
Sprache:English
Veröffentlicht: Elsevier 2017