Negative symptoms and cognitive impairment are associated with distinct motivational deficits in treatment resistant schizophrenia

Background: Motivational deficits are a central feature of the negative syndrome in schizophrenia. They have consistently been associated with reduced willingness to expend physical effort in return for monetary rewards on effort based decision making (EBDM) paradigms. Nevertheless, the mechanisms u...

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Bibliographic Details
Main Authors: Saleh, Y, Jarratt-Barnham, I, Petitet, P, Fernandez-Egea, E, Manohar, SG, Husain, M
Format: Journal article
Language:English
Published: Springer Nature [academic journals on nature.com] 2023