Severe pandemic H1N1 2009 infection is associated with transient NK and T deficiency and aberrant CD8 responses.

BACKGROUND: It is unclear why the severity of influenza varies in healthy adults or why the burden of severe influenza shifts to young adults when pandemic strains emerge. One possibility is that cross-protective T cell responses wane in this age group in the absence of recent infection. We therefo...

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Bibliographic Details
Main Authors: Fox, A, Le, N, Horby, P, van Doorn, H, Nguyen, V, Nguyen, H, Nguyen, T, Vu, D, Nguyen, M, Diep, N, Bich, V, Huong, H, Taylor, W, Farrar, J, Wertheim, H
Format: Journal article
Language:English
Published: Public Library of Science 2012