Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A.

ATP-sensitive K(+) channels are the target for K(+) channel openers such as pinacidil. These channels are formed from pore-forming Kir6. 2 and regulatory sulfonylurea receptor (SUR) subunits. Pinacidil activates channels containing SUR2A (heart, skeletal muscle), but not those containing SUR1 (beta...

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Những tác giả chính: Gribble, F, Reimann, F, Ashfield, R, Ashcroft, F
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2000