Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A.

Nucleotide modulation of pinacidil stimulation of the cloned K(ATP) channel Kir6.2/SUR2A.

ATP-sensitive K(+) channels are the target for K(+) channel openers such as pinacidil. These channels are formed from pore-forming Kir6. 2 and regulatory sulfonylurea receptor (SUR) subunits. Pinacidil activates channels containing SUR2A (heart, skeletal muscle), but not those containing SUR1 (beta...

Full description

Bibliographic Details
Main Authors:	Gribble, F, Reimann, F, Ashfield, R, Ashcroft, F
Format:	Journal article
Language:	English
Published:	2000

Similar Items

Nucleotide modulation of pinacidil stimulation of cloned KATP channels
by: Reimann, F, et al.
Published: (2000)

Differential response of K(ATP) channels containing SUR2A or SUR2B subunits to nucleotides and pinacidil.
by: Reimann, F, et al.
Published: (2000)

Effects of mitiglinide (S 21403) on Kir6.2/SUR1, Kir6.2/SUR2A and Kir6.2/SUR2B types of ATP-sensitive potassium channel.
by: Reimann, F, et al.
Published: (2001)

Glimepiride block of Kir6.2/SUR1 Kir6.2/SUR2A and Kir6.2/SUR2A and Kir6.2/SUR2B K-ATP channels.
by: Ashcroft, F, et al.
Published: (2001)

Time-dependent activation of Kir6.2/SUR2A channels but not Kir6.2/SUR1 channels in the presence of ATP
by: Ashcroft, F, et al.
Published: (2001)

Time-dependent activation of KIR6.2/SUR2A channels but not KIR6.2/SUR1 channels in the presence of MgATP
by: Song, D, et al.
Published: (2001)

The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP.
by: Reimann, F, et al.
Published: (1999)

Regulation of K-ATP channels by nucleotides and drugs
by: Gribble, F, et al.
Published: (2000)

Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
by: Proks, P, et al.
Published: (1999)

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor.
by: Tucker, S, et al.
Published: (1997)

Structure-function studies of the fast gating kinetics of the cloned ATP-sensitive potassium channel, Kir6.2/SUR1
by: Proks, P, et al.
Published: (2001)

A novel SUR1/Kir6.2 specific K-ATP channel opener
by: Dabrowski, M, et al.
Published: (2001)

The N-terminus of Kir6.2 is involved in coupling to SUR1
by: Reimann, F, et al.
Published: (1999)

Pyridine nucleotide regulation of the KATP channel Kir6.2/SUR1 expressed in Xenopus oocytes.
by: Dabrowski, M, et al.
Published: (2003)

Mapping the architecture of the ATP-binding site of Kir6.2
by: Dabrowski, M, et al.
Published: (2002)

Interactions between tolbutamide and nucleotides on cloned K-ATP channels.
by: Gribble, F, et al.
Published: (1997)

The Kir6.2-F333I mutation differentially modulates K-ATP channels composed of SUR1 or SUR2 subunits
by: Tammaro, P, et al.
Published: (2007)

The Kir6.2-F333I mutation differentially modulates K ATP channels composed of SUR1 and SUR2 subunits
by: Tammaro, P, et al.
Published: (2007)

Differential activation of cloned K-ATP channels by nicorandil
by: Reimann, F, et al.
Published: (2001)

A mutation in the ATP-binding site of the Kir6.2 subunit of the KATP channel alters coupling with the SUR2A subunit.
by: Tammaro, P, et al.
Published: (2007)

Expression of the cloned beta-cell ATP-sensitive potassium channel in Xenopus oocytes
by: Gribble, F, et al.
Published: (1996)

Mapping the architecture of the ATP-binding site of the KATP channel subunit Kir6.2.
by: Dabrowski, M, et al.
Published: (2004)

Identification of residues contributing to the ATP binding site of Kir6.2.
by: Trapp, S, et al.
Published: (2003)

Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas.
by: Lippiat, J, et al.
Published: (2002)

Focus on Kir6.2: a key component of the ATP-sensitive potassium channel.
by: Haider, S, et al.
Published: (2005)

Screening for mutations in the Kir6.2 subunit of the beta-cell K-ATP channel
by: Sakura, H, et al.
Published: (1996)

Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channel.
by: Ashfield, R, et al.
Published: (1999)

Overlapping distribution of K(ATP) channel-forming Kir6.2 subunit and the sulfonylurea receptor SUR1 in rodent brain.
by: Karschin, C, et al.
Published: (1997)

Identification of the high affinity tolbutamide site on the SUR1 subunit of the K-ATP channel
by: Gribble, F, et al.
Published: (1999)

Kir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2-SUR1 interactions.
by: Tammaro, P, et al.
Published: (2005)

Behavioral phenotyping of mice lacking the K ATP channel subunit Kir6.2.
by: Deacon, R, et al.
Published: (2006)

Behavioral phenotyping of mice lacking the K ATP channel subunit Kir6.2.
by: Deacon, R, et al.
Published: (2006)

Direct photoaffinity labeling of the Kir6.2 subunit of the ATP-sensitive K+ channel by 8-azido-ATP.
by: Tanabe, K, et al.
Published: (1999)

Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor.
by: Reimann, F, et al.
Published: (1999)

Association studies of variants in promoter and coding regions of beta-cell ATP-sensitive K-channel genes SUR1 and Kir6.2 with Type 2 diabetes mellitus (UKPDS 53).
by: Gloyn, A, et al.
Published: (2001)

Kir6.2-dependent high-affinity repaglinide binding to beta-cell K(ATP) channels.
by: Hansen, A, et al.
Published: (2005)

Properties of cloned ATP-sensitive K+ currents expressed in Xenopus oocytes.
by: Gribble, F, et al.
Published: (1997)

INWARDLY RECTIFYING K+ CURRENTS IN OOCYTES CO-EXPRESSING KIR3.1 AND KIR3.2
by: Ammala, C, et al.
Published: (1995)

Phentolamine block of KATP channels is mediated by Kir6.2.
by: Proks, P, et al.
Published: (1997)

The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation.
by: Gribble, F, et al.
Published: (1997)