The role of Nef protein in the pathogenesis of HIV infection

<p>Human Immunodeficiency virus (HIV-1) uses various mechanisms to evade immune recognition by cytotoxic T cells. Down-regulation of Human Leucocyte Antigen class I (HLA-I) by the viral protein Nef is one such important mechanism. HLA-A and B are believed to be down-regulated by Nef while HLA-...

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Bibliographic Details
Main Author: Rajapaksa, U
Other Authors: Dong, T
Format: Thesis
Language:English
Published: 2013
Subjects: