The role of Nef protein in the pathogenesis of HIV infection

The role of Nef protein in the pathogenesis of HIV infection

<p>Human Immunodeficiency virus (HIV-1) uses various mechanisms to evade immune recognition by cytotoxic T cells. Down-regulation of Human Leucocyte Antigen class I (HLA-I) by the viral protein Nef is one such important mechanism. HLA-A and B are believed to be down-regulated by Nef while HLA-...

Descripció completa

Dades bibliogràfiques
Autor principal:	Rajapaksa, U
Altres autors:	Dong, T
Format:	Thesis
Idioma:	English
Publicat:	2013
Matèries:	HIV/AIDS Viruses Immunology

Ítems similars

The Nef activity on HIV-1 infectivity
per: Stéphane eBasmaciogullari, et al.
Publicat: (2014-05-01)

Anti-HIV antibody development up to 1 year after antiretroviral therapy initiation in acute HIV infection
per: Julie L. Mitchell, et al.
Publicat: (2022-01-01)

Assessment of HIV-1 integration in tissues and subsets across infection stages
per: Vincent H. Wu, et al.
Publicat: (2020-12-01)

IL-15 enhances HIV-1 infection by promoting survival and proliferation of CCR5+CD4+ T cells
per: Yuhao Li, et al.
Publicat: (2023-04-01)

Characterisation of the HIV-1 reservoir and the potential for viral eradication
per: Williams, J, et al.
Publicat: (2014)

Natural and therapy-induced immune control of HIV-1
per: Yager, N
Publicat: (2011)

Identification of immunological targets for HIV-1 vaccine and cure strategies
per: Hancock, G
Publicat: (2014)

The impact of host and therapy mediated selection on HIV-1 evolution
per: Huang, K
Publicat: (2010)

The TLR7/IRF-5 axis sensitizes memory CD4+ T cells to Fas-mediated apoptosis during HIV-1 infection
per: Liseth Carmona-Pérez, et al.
Publicat: (2023-07-01)

Definition of the early HIV-1 signalosome in dendritic cells
per: Khatamzas, E
Publicat: (2013)

Higher circulating intermediate monocytes are associated with cognitive function in women with HIV
per: Rebecca T. Veenhuis, et al.
Publicat: (2021-06-01)

T-cell receptor (TCR) usage in HIV-2 infection
per: Moysi, E
Publicat: (2012)

Population-specific HLA impact in immune control of HIV in Mexico and non-Mexican HIV infected cohorts
per: Juarez Molina, CI
Publicat: (2014)

Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype
per: Vinicius Vieira, et al.
Publicat: (2023-02-01)

Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition
per: Alexandra Schuetz, et al.
Publicat: (2023-08-01)

Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control
per: Federico Perdomo-Celis, et al.
Publicat: (2022-06-01)

The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells
per: Dennis C. Copertino Jr., et al.
Publicat: (2023-09-01)

A functional and structural study of HLA-B*2705 restricted CTL responses associated with delayed HIV-1 disease progression
per: Pymm, PG
Publicat: (2012)

Distinct patterns of natural selection in the reverse transcriptase gene of HIV-1 in the presence and absence of antiretroviral therapy
per: Leal, É, et al.
Publicat: (2004)

Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivo
per: Asquith, B, et al.
Publicat: (2006)

Immunodominant CD8+ T cell responses to HIV-1 infection - 'The good and the bad'
per: Culshaw, A
Publicat: (2011)

Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection
per: Sheikh Abdul Rahman, et al.
Publicat: (2022-04-01)

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
per: Justin Harper, et al.
Publicat: (2022-04-01)

A study of the phenotype and function of HLA-C restricted CD8 T cells in HIV-1 infection
per: Corrah, TW
Publicat: (2011)

IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health
per: Louise A. Swainson, et al.
Publicat: (2022-03-01)

HIV-1 transmission between T cells and macrophages: consequences for viral pathogenesis.
per: Baxter, A
Publicat: (2013)

The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells
per: Gabriel Duette, et al.
Publicat: (2022-04-01)

Architecture of the HIV-1 glycan shield
per: Pritchard, L
Publicat: (2014)

Pathogenesis of HIV infection
per: Hassan M. Naif
Publicat: (2013-06-01)

HIV-1 induction of macrophage immune mediators
per: Dacon, C
Publicat: (2019)

HIV-1 Nef: a multifaceted modulator of T cell receptor signaling
per: Abraham Libin, et al.
Publicat: (2012-12-01)

The design and development of an HIV-1 vaccine to elicit a broadly neutralising antibody response
per: Wan, L, et al.
Publicat: (2012)

Factors influencing maternal microchimerism throughout infancy and its impact on infant T cell immunity
per: Christina Balle, et al.
Publicat: (2022-07-01)

Differential localization and limited cytotoxic potential of duodenal CD8+ T cells
per: Leonard Mvaya, et al.
Publicat: (2022-02-01)

Effect of immunological non-response on incidence of Non-AIDS events in people living with HIV: A retrospective multicenter cohort study in Taiwan
per: Chia-Hui Wen, et al.
Publicat: (2023-10-01)

Imaging of HIV-1 spread from T cells and Macrophages to Astrocytes
per: Do, T
Publicat: (2014)

The impact of HIV-1 disease and its treatment on mycobacterium tuberculosis-specific immunity
per: Murray, L
Publicat: (2014)

Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor
per: Lori A. Emert-Sedlak, et al.
Publicat: (2022-09-01)

Symptomatic profile of infected individuals with HIV/AIDS in a physiotherapy department
per: Tamaiara Barbosa do Amorim, et al.

Development and the HIV epidemic : a forward-looking evaluation of the approach of the UNDP HIV and Development Programme /
per: Parnell, Bruce
Publicat: (1996)