The role of Nef protein in the pathogenesis of HIV infection

The role of Nef protein in the pathogenesis of HIV infection

<p>Human Immunodeficiency virus (HIV-1) uses various mechanisms to evade immune recognition by cytotoxic T cells. Down-regulation of Human Leucocyte Antigen class I (HLA-I) by the viral protein Nef is one such important mechanism. HLA-A and B are believed to be down-regulated by Nef while HLA-...

Fuld beskrivelse

Bibliografiske detaljer
Hovedforfatter:	Rajapaksa, U
Andre forfattere:	Dong, T
Format:	Thesis
Sprog:	English
Udgivet:	2013
Fag:	HIV/AIDS Viruses Immunology

Lignende værker

The Nef activity on HIV-1 infectivity
af: Stéphane eBasmaciogullari, et al.
Udgivet: (2014-05-01)

Anti-HIV antibody development up to 1 year after antiretroviral therapy initiation in acute HIV infection
af: Julie L. Mitchell, et al.
Udgivet: (2022-01-01)

Assessment of HIV-1 integration in tissues and subsets across infection stages
af: Vincent H. Wu, et al.
Udgivet: (2020-12-01)

Chronic HIV infection induces transcriptional and functional reprogramming of innate immune cells
af: Wouter A. van der Heijden, et al.
Udgivet: (2021-04-01)

IL-15 enhances HIV-1 infection by promoting survival and proliferation of CCR5+CD4+ T cells
af: Yuhao Li, et al.
Udgivet: (2023-04-01)

Characterisation of the HIV-1 reservoir and the potential for viral eradication
af: Williams, J, et al.
Udgivet: (2014)

Natural and therapy-induced immune control of HIV-1
af: Yager, N
Udgivet: (2011)

Identification of immunological targets for HIV-1 vaccine and cure strategies
af: Hancock, G
Udgivet: (2014)

The impact of host and therapy mediated selection on HIV-1 evolution
af: Huang, K
Udgivet: (2010)

The TLR7/IRF-5 axis sensitizes memory CD4+ T cells to Fas-mediated apoptosis during HIV-1 infection
af: Liseth Carmona-Pérez, et al.
Udgivet: (2023-07-01)

Definition of the early HIV-1 signalosome in dendritic cells
af: Khatamzas, E
Udgivet: (2013)

Higher circulating intermediate monocytes are associated with cognitive function in women with HIV
af: Rebecca T. Veenhuis, et al.
Udgivet: (2021-06-01)

T-cell receptor (TCR) usage in HIV-2 infection
af: Moysi, E
Udgivet: (2012)

TCF-1 regulates HIV-specific CD8+ T cell expansion capacity
af: Rachel L. Rutishauser, et al.
Udgivet: (2021-02-01)

Population-specific HLA impact in immune control of HIV in Mexico and non-Mexican HIV infected cohorts
af: Juarez Molina, CI
Udgivet: (2014)

Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype
af: Vinicius Vieira, et al.
Udgivet: (2023-02-01)

Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition
af: Alexandra Schuetz, et al.
Udgivet: (2023-08-01)

Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control
af: Federico Perdomo-Celis, et al.
Udgivet: (2022-06-01)

The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells
af: Dennis C. Copertino Jr., et al.
Udgivet: (2023-09-01)

HIV-specific T cell responses reflect substantive in vivo interactions with antigen despite long-term therapy
af: Eva M. Stevenson, et al.
Udgivet: (2021-02-01)

A functional and structural study of HLA-B*2705 restricted CTL responses associated with delayed HIV-1 disease progression
af: Pymm, PG
Udgivet: (2012)

Distinct patterns of natural selection in the reverse transcriptase gene of HIV-1 in the presence and absence of antiretroviral therapy
af: Leal, É, et al.
Udgivet: (2004)

Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivo
af: Asquith, B, et al.
Udgivet: (2006)

Immunodominant CD8+ T cell responses to HIV-1 infection - 'The good and the bad'
af: Culshaw, A
Udgivet: (2011)

Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection
af: Sheikh Abdul Rahman, et al.
Udgivet: (2022-04-01)

Epigenetic silencing of CD4 expression in nonpathogenic SIV infection in African green monkeys
af: Joseph C. Mudd, et al.
Udgivet: (2020-09-01)

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
af: Justin Harper, et al.
Udgivet: (2022-04-01)

A study of the phenotype and function of HLA-C restricted CD8 T cells in HIV-1 infection
af: Corrah, TW
Udgivet: (2011)

IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health
af: Louise A. Swainson, et al.
Udgivet: (2022-03-01)

HIV-1 transmission between T cells and macrophages: consequences for viral pathogenesis.
af: Baxter, A
Udgivet: (2013)

Intestinal parasitic infections in HIV/AIDS patients: epidemiological, nutritional and immunological aspects
af: FAM Amâncio, et al.
Udgivet: (2012-01-01)

Architecture of the HIV-1 glycan shield
af: Pritchard, L
Udgivet: (2014)

The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells
af: Gabriel Duette, et al.
Udgivet: (2022-04-01)

HIV-1 induction of macrophage immune mediators
af: Dacon, C
Udgivet: (2019)

Pathogenesis of HIV infection
af: Hassan M. Naif
Udgivet: (2013-06-01)

HIV-1 Nef: a multifaceted modulator of T cell receptor signaling
af: Abraham Libin, et al.
Udgivet: (2012-12-01)

The design and development of an HIV-1 vaccine to elicit a broadly neutralising antibody response
af: Wan, L, et al.
Udgivet: (2012)

Factors influencing maternal microchimerism throughout infancy and its impact on infant T cell immunity
af: Christina Balle, et al.
Udgivet: (2022-07-01)

Differential localization and limited cytotoxic potential of duodenal CD8+ T cells
af: Leonard Mvaya, et al.
Udgivet: (2022-02-01)

Effect of immunological non-response on incidence of Non-AIDS events in people living with HIV: A retrospective multicenter cohort study in Taiwan
af: Chia-Hui Wen, et al.
Udgivet: (2023-10-01)