The role of Nef protein in the pathogenesis of HIV infection

The role of Nef protein in the pathogenesis of HIV infection

<p>Human Immunodeficiency virus (HIV-1) uses various mechanisms to evade immune recognition by cytotoxic T cells. Down-regulation of Human Leucocyte Antigen class I (HLA-I) by the viral protein Nef is one such important mechanism. HLA-A and B are believed to be down-regulated by Nef while HLA-...

书目详细资料
主要作者:	Rajapaksa, U
其他作者:	Dong, T
格式:	Thesis
语言:	English
出版:	2013
主题:	HIV/AIDS Viruses Immunology

相似书籍

The Nef activity on HIV-1 infectivity
由: Stéphane eBasmaciogullari, et al.
出版: (2014-05-01)

Anti-HIV antibody development up to 1 year after antiretroviral therapy initiation in acute HIV infection
由: Julie L. Mitchell, et al.
出版: (2022-01-01)

Assessment of HIV-1 integration in tissues and subsets across infection stages
由: Vincent H. Wu, et al.
出版: (2020-12-01)

IL-15 enhances HIV-1 infection by promoting survival and proliferation of CCR5+CD4+ T cells
由: Yuhao Li, et al.
出版: (2023-04-01)

Characterisation of the HIV-1 reservoir and the potential for viral eradication
由: Williams, J, et al.
出版: (2014)

Natural and therapy-induced immune control of HIV-1
由: Yager, N
出版: (2011)

Identification of immunological targets for HIV-1 vaccine and cure strategies
由: Hancock, G
出版: (2014)

The impact of host and therapy mediated selection on HIV-1 evolution
由: Huang, K
出版: (2010)

The TLR7/IRF-5 axis sensitizes memory CD4+ T cells to Fas-mediated apoptosis during HIV-1 infection
由: Liseth Carmona-Pérez, et al.
出版: (2023-07-01)

Definition of the early HIV-1 signalosome in dendritic cells
由: Khatamzas, E
出版: (2013)

Higher circulating intermediate monocytes are associated with cognitive function in women with HIV
由: Rebecca T. Veenhuis, et al.
出版: (2021-06-01)

T-cell receptor (TCR) usage in HIV-2 infection
由: Moysi, E
出版: (2012)

Population-specific HLA impact in immune control of HIV in Mexico and non-Mexican HIV infected cohorts
由: Juarez Molina, CI
出版: (2014)

Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype
由: Vinicius Vieira, et al.
出版: (2023-02-01)

Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition
由: Alexandra Schuetz, et al.
出版: (2023-08-01)

Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control
由: Federico Perdomo-Celis, et al.
出版: (2022-06-01)

The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells
由: Dennis C. Copertino Jr., et al.
出版: (2023-09-01)

A functional and structural study of HLA-B*2705 restricted CTL responses associated with delayed HIV-1 disease progression
由: Pymm, PG
出版: (2012)

Distinct patterns of natural selection in the reverse transcriptase gene of HIV-1 in the presence and absence of antiretroviral therapy
由: Leal, É, et al.
出版: (2004)

Inefficient cytotoxic T lymphocyte-mediated killing of HIV-1-infected cells in vivo
由: Asquith, B, et al.
出版: (2006)

Immunodominant CD8+ T cell responses to HIV-1 infection - 'The good and the bad'
由: Culshaw, A
出版: (2011)

Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection
由: Sheikh Abdul Rahman, et al.
出版: (2022-04-01)

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy
由: Justin Harper, et al.
出版: (2022-04-01)

A study of the phenotype and function of HLA-C restricted CD8 T cells in HIV-1 infection
由: Corrah, TW
出版: (2011)

IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health
由: Louise A. Swainson, et al.
出版: (2022-03-01)

HIV-1 transmission between T cells and macrophages: consequences for viral pathogenesis.
由: Baxter, A
出版: (2013)

The HIV-1 proviral landscape reveals that Nef contributes to HIV-1 persistence in effector memory CD4+ T cells
由: Gabriel Duette, et al.
出版: (2022-04-01)

Architecture of the HIV-1 glycan shield
由: Pritchard, L
出版: (2014)

Pathogenesis of HIV infection
由: Hassan M. Naif
出版: (2013-06-01)

HIV-1 induction of macrophage immune mediators
由: Dacon, C
出版: (2019)

HIV-1 Nef: a multifaceted modulator of T cell receptor signaling
由: Abraham Libin, et al.
出版: (2012-12-01)

The design and development of an HIV-1 vaccine to elicit a broadly neutralising antibody response
由: Wan, L, et al.
出版: (2012)

Factors influencing maternal microchimerism throughout infancy and its impact on infant T cell immunity
由: Christina Balle, et al.
出版: (2022-07-01)

Differential localization and limited cytotoxic potential of duodenal CD8+ T cells
由: Leonard Mvaya, et al.
出版: (2022-02-01)

Effect of immunological non-response on incidence of Non-AIDS events in people living with HIV: A retrospective multicenter cohort study in Taiwan
由: Chia-Hui Wen, et al.
出版: (2023-10-01)

Imaging of HIV-1 spread from T cells and Macrophages to Astrocytes
由: Do, T
出版: (2014)

The impact of HIV-1 disease and its treatment on mycobacterium tuberculosis-specific immunity
由: Murray, L
出版: (2014)

Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor
由: Lori A. Emert-Sedlak, et al.
出版: (2022-09-01)

Symptomatic profile of infected individuals with HIV/AIDS in a physiotherapy department
由: Tamaiara Barbosa do Amorim, et al.

Development and the HIV epidemic : a forward-looking evaluation of the approach of the UNDP HIV and Development Programme /
由: Parnell, Bruce
出版: (1996)