The ratio of osteocytic incorporation to bone matrix formation in femoral neck cancellous bone: an enhanced osteoblast work rate in the vicinity of hip osteoarthritis.

Recently it has been shown that an inactivating mutation in the TGFb-SMAD3 signaling pathway, which increases the conversion of osteoblasts to osteocytes, is accompanied by bone loss combined with increased osteocyte density. We hypothesized that increased matrix TGFb, known to occur in osteoarthrit...

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Bibliographic Details
Main Authors: Jordan, G, Loveridge, N, Power, J, Clarke, M, Parker, M, Reeve, J
Format: Journal article
Language:English
Published: 2003