Detecting natural selection in RNA virus populations using sequence summary statistics
At present, most analyses that aim to detect the action of natural selection upon viral gene sequences use phylogenetic estimates of the ratio of silent to replacement mutations. Such methods, however, are impractical to compute on large data sets comprising hundreds of viral genomes, which are beco...
主要な著者: | , , |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
Elsevier
2010
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