Novel regulation of SRC family kinase signalling by RASSF1 isoforms

<p>RASSF1A is a tumour suppressor, the silencing of which occurs through promoter methylation in a variety of human cancers. Loss of RASSF1A is associated with decreased sensitivity to DNA damaging agents and worse prognosis in breast, colon and lung cancers amongst others. RASSF1A functions i...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awdur: Scrace, SF
Awduron Eraill: O'Neill, E
Fformat: Traethawd Ymchwil
Iaith:English
Cyhoeddwyd: 2013
Pynciau: