Novel regulation of SRC family kinase signalling by RASSF1 isoforms

<p>RASSF1A is a tumour suppressor, the silencing of which occurs through promoter methylation in a variety of human cancers. Loss of RASSF1A is associated with decreased sensitivity to DNA damaging agents and worse prognosis in breast, colon and lung cancers amongst others. RASSF1A functions i...

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Bibliographic Details
Main Author: Scrace, SF
Other Authors: O'Neill, E
Format: Thesis
Language:English
Published: 2013
Subjects: