Novel regulation of SRC family kinase signalling by RASSF1 isoforms
<p>RASSF1A is a tumour suppressor, the silencing of which occurs through promoter methylation in a variety of human cancers. Loss of RASSF1A is associated with decreased sensitivity to DNA damaging agents and worse prognosis in breast, colon and lung cancers amongst others. RASSF1A functions i...
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Format: | Thesis |
Language: | English |
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2013
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