Tumor defense by murine cytotoxic T cells specific for peptide bound to nonclassical MHC class I.

Cytotoxic T Cells (CTLs) can exhibit considerable antitumor activity. Thus far, the characterized tumor peptide antigens recognized by CTLs are all presented by classical MHC class Ia molecules [human lymphocyte antigen A (HLA-A), HLA-B, and HLA-C in humans and H-2K, H-2D, and H-2L in mice]. Here we...

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Bibliographic Details
Main Authors: Griffiths, E, Ong, H, Soloski, M, Bachmann, M, Ohashi, P, Speiser, D
Format: Journal article
Language:English
Published: 1998