Selective effects of the APOE epsilon4 allele on presynaptic cholinergic markers in the neocortex of Alzheimer's disease.

The effects of the APOE epsilon4 allele on a range of pre- and postsynaptic cholinergic markers were studied in a cohort of community-based Alzheimer's disease (AD) patients. Compared with age-matched controls, the postmortem AD neocortex showed decreased choline acetyltransferase (ChAT) and ac...

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Detalles Bibliográficos
Main Authors: Lai, M, Tsang, S, Garcia-Alloza, M, Minger, S, Nicoll, J, Esiri, M, Wong, P, Chen, C, Ramírez, M, Francis, P
Formato: Journal article
Idioma:English
Publicado: 2006