Diverse hepatitis C virus glycoproteins mediate viral infection in a CD81-dependent manner.

We recently reported that retroviral pseudotypes bearing the hepatitis C virus (HCV) strain H and Con1 glycoproteins, genotype 1a and 1b, respectively, require CD81 as a coreceptor for virus-cell entry and infection. Soluble truncated E2 cloned from a number of diverse HCV genotypes fail to interact...

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Những tác giả chính: McKeating, J, Zhang, L, Logvinoff, C, Flint, M, Zhang, J, Yu, J, Butera, D, Ho, D, Dustin, L, Rice, C, Balfe, P
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2004