Elevation of iron storage in humans attenuates the pulmonary vascular response to hypoxia

Sustained hypoxia over several hours induces a progressive rise in pulmonary artery systolic pressure (PASP). Administration of intravenous iron immediately prior to the hypoxia exposure abrogates this effect, suggesting that manipulation of iron stores may modify hypoxia-induced pulmonary hypertens...

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Bibliographic Details
Main Authors: Bart, N, Curtis, M, Cheng, H, Hungerford, S, McLaren, R, Petousi, M, Dorrington, K, Robbins, P
Format: Journal article
Language:English
Published: American Physiological Society 2016