Enhanced apoptotic activity of a structurally optimized form of galectin-1.

Galectin-1 is a homodimeric protein with potent anti-inflammatory properties due to its ability to induce apoptosis in thymocytes and T cells. The galectin-1 subunits are not covalently linked but the monomers are in a dynamic equilibrium with the dimeric form. Since the affinity of the monomers for...

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Bibliographic Details
Main Authors: Bättig, P, Saudan, P, Gunde, T, Bachmann, M
Format: Journal article
Language:English
Published: 2004