Enhanced apoptotic activity of a structurally optimized form of galectin-1.
Galectin-1 is a homodimeric protein with potent anti-inflammatory properties due to its ability to induce apoptosis in thymocytes and T cells. The galectin-1 subunits are not covalently linked but the monomers are in a dynamic equilibrium with the dimeric form. Since the affinity of the monomers for...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2004
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