The de novo selection of drug-resistant malaria parasites.
Antimalarial drug resistance emerges de novo predominantly in areas of low malaria transmission. Because of the logarithmic distribution of parasite numbers in human malaria infections, inadequately treated high biomass infections are a major source of de novo antimalarial resistance, whereas use of...
Main Authors: | , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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