D-chiro-inositol ribophostin: a highly potent agonist at D-myo-inositol 1,4,5-trisphosphate receptors: synthesis and biological activities
Analogues of the Ca2+-releasing intracellular messenger D-myo-inositol 1,4,5-trisphosphate [1, Ins(1,4,5)P3] are important synthetic targets. Replacement of the α-glucopyranosyl motif in the natural product mimic adenophostin 2 by D-chiro-inositol in D-chiro-inositol adenophostin 4 increased potency...
Autori principali: | , , , , , |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
American Chemical Society
2020
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