D-chiro-inositol ribophostin: a highly potent agonist at D-myo-inositol 1,4,5-trisphosphate receptors: synthesis and biological activities
Analogues of the Ca2+-releasing intracellular messenger D-myo-inositol 1,4,5-trisphosphate [1, Ins(1,4,5)P3] are important synthetic targets. Replacement of the α-glucopyranosyl motif in the natural product mimic adenophostin 2 by D-chiro-inositol in D-chiro-inositol adenophostin 4 increased potency...
| Main Authors: | , , , , , |
|---|---|
| 格式: | Journal article |
| 语言: | English |
| 出版: |
American Chemical Society
2020
|