Mucosal signatures of pathogenic T cells in HLA-B*27+ anterior uveitis and axial spondyloarthritis

HLA-B*27 was one of the first HLA alleles associated with an autoimmune disease, i.e., axial spondyloarthritis (axSpA) and acute anterior uveitis (B27AAU), which cause joint and eye inflammation, respectively. Gastrointestinal inflammation has been suggested as a trigger of axSpA. We recently identi...

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Bibliographic Details
Main Authors: Paley, MA, Yang, X, Hassman, LM, Penkava, F, Garner, LI, Paley, GL, Linskey, N, Agnew, R, Arantes de Faria, PH, Feng, A, Li, SY, Simone, D, Roberson, EDO, Ruzycki, PA, Esaulova, E, Laurent, J, Feigl-Lenzen, L, Springer, LE, Liu, C, Gillespie, GM, Bowness, P, Garcia, KC, Yokoyama, WM
Format: Journal article
Language:English
Published: American Society for Clinical Investigation 2024