Identification of the metabolites of ivermectin in humans

Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito‐lethal effect well beyond its biological half‐life, suggesting the presence of active slowly eliminated metabolites. Human liver microsomes, primary human hepatocytes, and...

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Bibliographic Details
Main Authors: Tipthara, P, Kobylinski, KC, Godejohann, M, Hanboonkunupakarn, B, Roth, A, Adams, JH, White, NJ, Jittamala, P, Day, NPJ, Tarning, J
Format: Journal article
Language:English
Published: Wiley 2021