Epitope specificity and relative clonal abundance do not affect CD8 differentiation patterns during lymphocytic choriomeningitis virus infection.

To evaluate the impact of immunodominance on CD8 T-cell properties, we compared the functional properties of dominant and subdominant populations in the response to lymphocytic choriomeningitis virus (LCMV). To improve functional discrimination, in addition to the usual tests of phenotype and functi...

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Bibliographic Details
Main Authors: Munitic, I, Decaluwe, H, Evaristo, C, Lemos, S, Wlodarczyk, M, Worth, A, Le Bon, A, Selin, L, Rivière, Y, Di Santo, J, Borrow, P, Rocha, B
Format: Journal article
Language:English
Published: 2009