A molecular mechanism of mitotic centrosome assembly in Drosophila

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both...

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Détails bibliographiques
Auteurs principaux: Conduit, PT, Richens, JH, Wainman, A, Holder, J, Vicente, CC, Pratt, MB, Dix, CI, Novak, ZA, Dobbie, IM, Schermelleh, L, Raff, JW
Format: Journal article
Langue:English
Publié: eLife Sciences Publications 2014