A molecular mechanism of mitotic centrosome assembly in Drosophila

A molecular mechanism of mitotic centrosome assembly in Drosophila

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Conduit, PT, Richens, JH, Wainman, A, Holder, J, Vicente, CC, Pratt, MB, Dix, CI, Novak, ZA, Dobbie, IM, Schermelleh, L, Raff, JW
التنسيق:	Journal article
اللغة:	English
منشور في:	eLife Sciences Publications 2014

مواد مشابهة

A molecular mechanism of mitotic centrosome assembly in Drosophila
حسب: Paul T Conduit, وآخرون
منشور في: (2014-08-01)

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منشور في: (2015)

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حسب: Gartenmann, L, وآخرون
منشور في: (2020)

Different Drosophila cell types exhibit differences in mitotic centrosome assembly dynamics.
حسب: Conduit, P, وآخرون
منشور في: (2015)

Structural basis for mitotic centrosome assembly in flies
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منشور في: (2017)

Evidence that a positive feedback loop drives centrosome maturation in fly embryos
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منشور في: (2019)

Centrosome function and assembly in animal cells
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منشور في: (2015)

Re-examining the role of Drosophila Sas-4 in centrosome assembly using two-colour-3D-SIM FRAP
حسب: Paul T Conduit, وآخرون
منشور في: (2015-11-01)

The centrosome-specific phosphorylation of Cnn by Polo/Plk1 drives Cnn scaffold assembly and centrosome maturation.
حسب: Conduit, P, وآخرون
منشور في: (2014)

Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes
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منشور في: (2025)

Cdk1 phosphorylates Drosophila Sas-4 to recruit Polo to daughter centrioles and convert them to centrosomes
حسب: Raff, J, وآخرون
منشور في: (2016)

Cnn dynamics drive centrosome size asymmetry to ensure daughter centriole retention in Drosophila neuroblasts.
حسب: Conduit, P, وآخرون
منشور في: (2010)

A positive feedback loop drives centrosome maturation in flies
حسب: Alvarez Rodrigo, I, وآخرون
منشور في: (2018)

Drosophila Ana1 is required for centrosome assembly and centriole elongation
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منشور في: (2016)

Asterless licenses daughter centrioles to duplicate for the first time in Drosophila embryos.
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منشور في: (2014)

Centrioles regulate centrosome size by controlling the rate of Cnn incorporation into the PCM.
حسب: Conduit, P, وآخرون
منشور في: (2010)

Evidence that a positive feedback loop drives centrosome maturation in fly embryos
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منشور في: (2019-09-01)

Ana1 helps recruit Polo to centrioles to promote mitotic PCM assembly and centriole elongation
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منشور في: (2021)

The Drosophila Pericentrin-like-protein (PLP) cooperates with Cnn to maintain the integrity of the outer PCM
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Centrosome loss or amplification does not dramatically perturb global gene expression in Drosophila.
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The dominant force of Centrobin in centrosome asymmetry.
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منشور في: (1997)

Centrioles generate a local pulse of Polo/PLK1 activity to initiate mitotic centrosome assembly
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منشور في: (2022)

Centrosomes have a role in regulating the destruction of cyclin B in early Drosophila embryos.
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منشور في: (2000)

Drosophila Cep135/Bld10 maintains proper centriole structure but is dispensable for cartwheel formation.
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LK6, a novel Drosophila protein kinase that is rapidly turned over and is associated with microtubules and centrosomes.
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منشور في: (1996)

Dissecting the function and assembly of acentriolar microtubule organizing centers in Drosophila cells in vivo
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LIMK1 regulates centrosome integrity and mitotic spindle positioning
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منشور في: (2015)

Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay
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منشور في: (2017-06-01)

The centrosomal protein CP190 regulates myosin function during early Drosophila development.
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منشور في: (2005)

The Drosophila centrosome-associated protein CP190 is essential for viability but not for cell division.
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Centrosomal and Non-Centrosomal Microtubule-Organizing Centers (MTOCs) in Drosophila melanogaster
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منشور في: (2018-08-01)

A genome-wide RNAi screen to dissect centriole duplication and centrosome maturation in Drosophila
حسب: Dobbelaere, J, وآخرون
منشور في: (2008)

Centrosomes and microtubules: wedded with a ring.
حسب: Raff, J
منشور في: (1996)

SAPs as a new model to probe the pathway of centriole and centrosome assembly
حسب: Wainman, A
منشور في: (2021)

Centrosomes and cancer: lessons from a TACC.
حسب: Raff, J
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Phase separation and the centrosome: a fait accompli?
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