A molecular mechanism of mitotic centrosome assembly in Drosophila

Centrosomes comprise a pair of centrioles surrounded by pericentriolar material (PCM). The PCM expands dramatically as cells enter mitosis, but it is unclear how this occurs. In this study, we show that the centriole protein Asl initiates the recruitment of DSpd-2 and Cnn to mother centrioles; both...

詳細記述

書誌詳細
主要な著者: Conduit, PT, Richens, JH, Wainman, A, Holder, J, Vicente, CC, Pratt, MB, Dix, CI, Novak, ZA, Dobbie, IM, Schermelleh, L, Raff, JW
フォーマット: Journal article
言語:English
出版事項: eLife Sciences Publications 2014