On-microscope staging of live cells reveals changes in the dynamics of transcriptional bursting during differentiation
Determining the mechanisms by which genes are switched on and off during development is a key aim of current biomedical research. Gene transcription has been widely observed to occur in a discontinuous fashion, with short bursts of activity interspersed with periods of inactivity. It is currently no...
Main Authors: | Jeziorska, DM, Tunnacliffe, EAJ, Brown, JM, Ayyub, H, Sloane-Stanley, J, Sharpe, JA, Lagerholm, BC, Babbs, C, Smith, AJH, Buckle, VJ, Higgs, DR |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2022
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Subjects: |
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