Investigation of a possible extended risk haplotype in the IL23R region associated with ankylosing spondylitis

The IL23R region on chromosome 1 exhibits complex associations with ankylosing spondylitis (AS). We used publicly available epigenomic information and historical genetic association data to identify a potential regulatory element (PRE) in the intergenic region between IL23R and IL12RB2, which includ...

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Bibliographic Details
Main Authors: Roberts, A, Vecellio, M, Cortes, A, Knight, J, Cohen, C, Wordsworth, B
Format: Journal article
Published: Nature Publishing Group 2017