Retention of uninfected red blood cells causing congestive splenomegaly is the major mechanism of anemia in malaria

Splenomegaly frequently occurs in patients with Plasmodium falciparum (Pf) or P. vivax (Pv) malarial anemia, but mechanisms underlying this co-occurrence are unclear. In malaria-endemic Papua, Indonesia, we prospectively analyzed red blood cell (RBC) concentrations in the spleen and spleen-mimetic r...

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Main Authors: Kho, S, Siregar, NC, Qotrunnada, L, Fricot, A, Sissoko, A, Shanti, PAI, Candrawati, F, Kambuaya, NN, Rini, H, Andries, B, Hardy, D, Margyaningsih, NI, Fadllan, F, Rahmayenti, DA, Puspitasari, AM, Leonardo, L, Yayang, BTG, Margayani, DS, Prayoga, P, Trianty, L, Kenangalem, E, Price, RN, Yeo, TW, Minigo, G, Noviyanti, R, Poespoprodjo, JR, Anstey, NM, Buffet, PA
Format: Journal article
Language:English
Published: Wiley 2023