Improved expression of secreted and membrane-targeted proteins in insect cells.

Secretory and membrane-bound proteins are generally produced in lower amounts in insect cells compared with cytoplasmic and nuclear proteins. There may be many reasons for this, including degradation of recombinant proteins by proteases, competition for cellular resources between native and recombin...

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Bibliographic Details
Main Authors: Hitchman, R, Possee, R, Siaterli, E, Richards, K, Clayton, A, Bird, L, Owens, R, Carpentier, D, King, F, Danquah, J, Spink, K, King, L
Format: Journal article
Language:English
Published: 2010