The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data

The Effect of Dosing Regimens on the Antimalarial Efficacy of Dihydroartemisinin-Piperaquine: A Pooled Analysis of Individual Patient Data

Background:Dihydroartemisinin-piperaquine (DP) is increasingly recommended for antimalarial treatment in many endemic countries; however, concerns have been raised over its potential under dosing in young children. We investigated the influence of different dosing schedules on DP's clinical eff...

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Main Authors: Achan, J, Adam, I, Arinaitwe, E, Ashley, E, Awab, G, Ba, MS, Barnes, K, Bassat, Q, Borrmann, S, Bousema, T, Dahal, P, D'Alessandro, U, Davis, T, Dondorp, A, Dorsey, G, Drakeley, C, Fanello, C, Faye, B, Flegg, J, Gaye, O, Gething, P, Gonzalez, R, Guerin, P, Hay, S, Hien, T, Janssens, B, Kamya, MR, Karema, C, Karunajeewa, H, Kone, M, Lell, B, Marsh, K, Mayxay, M, Menendez, C, Mens, P, Meremikwu, M, Moreira, C, Mueller, I, Nabasumba, C, Nambozi, M, Ndiaye, J, Newton, P, Nguyen, T, Nosten, F, Nsanzabana, C, Omar, SA, Ouedraogo, J, Penali, L, Pene, M, Phyo, A, Piola, P, Price, R, Sasithon, P, Rosenthal, P, Same-Ekobo, A, Sawa, P, Schallig, H, Shekalaghe, SA, Sibley, C, Smith, J, Smithuis, F, Some, A, Stepniewska, K, Talisuna, A, Tarning, J, Tjitra, E, Tine, R, Tinto, H, Valecha, N, Van Herp, M, Van Vugt, M, White, N, Woodrow, C, Yavo, W, Yeka, A, Zongo, I, Grp, W
Format: Journal article
Published: Public Library of Science 2013

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