Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke

Asymmetric and symmetric dimethylarginines (ADMA and SDMA) impair nitric oxide bioavailability and have been implicated in the pathogenesis of atrial fibrillation (AF). Alanine-glyoxylate aminotransferase 2 (AGXT2) is the only enzyme capable of metabolizing both of the dimethylarginines. We hypothes...

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Bibliografiska uppgifter
Huvudupphovsmän:	Seppälä, I, Kleber, M, Bevan, S, Lyytikäinen, L, Oksala, N, Hernesniemi, J, Mäkelä, K, Rothwell, P, Sudlow, C, Dichgans, M, Mononen, N, Vlachopoulou, E, Sinisalo, J, Delgado, G, Laaksonen, R, Koskinen, T, Scharnagl, H, Kähönen, M, Markus, H, März, W, Lehtimäki, T
Materialtyp:	Journal article
Språk:	English
Publicerad:	2016

Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke

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