Structure and dynamics of the membrane-bound cytochrome P450 2C9
The microsomal, membrane-bound, human cytochrome P450 (CYP) 2C9 is a liver-specific monooxygenase essential for drug metabolism. CYPs require electron transfer from the membrane-bound CYP reductase (CPR) for catalysis. The structural details and functional relevance of the CYP-membrane interaction a...
Main Authors: | , , , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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