Structure and dynamics of the membrane-bound cytochrome P450 2C9

The microsomal, membrane-bound, human cytochrome P450 (CYP) 2C9 is a liver-specific monooxygenase essential for drug metabolism. CYPs require electron transfer from the membrane-bound CYP reductase (CPR) for catalysis. The structural details and functional relevance of the CYP-membrane interaction a...

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Bibliographic Details
Main Authors: Cojocaru, V, Balali-Mood, K, Sansom, M, Wade, R
Format: Journal article
Language:English
Published: 2011