Functional intracellular antibody fragments do not require invariant intra-domain disulfide bonds.
Intracellular antibody fragments that interfere with molecular interactions inside cells are valuable in investigation of interactomes and in therapeutics, but their application demands that they function in the reducing cellular milieu. We show here a 2.7-A crystal structure of intracellular antibo...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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