The role of electrostatics in colicin nuclease domain translocation into bacterial cells.

The mechanism(s) by which nuclease colicins translocate distinct cytotoxic enzymes (DNases, rRNases, and tRNases) to the cytoplasm of Escherichia coli is unknown. Previous in vitro investigations on isolated colicin nuclease domains have shown that they have a strong propensity to associate with ani...

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Bibliographic Details
Main Authors: Walker, D, Mosbahi, K, Vankemmelbeke, M, James, R, Kleanthous, K
Format: Journal article
Language:English
Published: 2007