Scc2 counteracts a Wapl-independent mechanism that releases cohesin from chromosomes during G1
Cohesin’s association with chromosomes is determined by loading dependent on the Scc2/4 complex and release due to Wapl. We show here that Scc2 also actively maintains cohesin on chromosomes during G1 in S. cerevisiae cells. It does so by blocking a Wapl-independent release reaction that requires op...
| Главные авторы: | , , , , , , , , |
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| Формат: | Journal article |
| Опубликовано: |
eLife Science Publications
2019
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