Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation.

Coordination of multiple enzyme activities by a single PCNA in archaeal Okazaki fragment maturation.

Chromosomal DNA replication requires one daughter strand-the lagging strand-to be synthesised as a series of discontinuous, RNA-primed Okazaki fragments, which must subsequently be matured into a single covalent DNA strand. Here, we describe the reconstitution of Okazaki fragment maturation in vitro...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Beattie, T, Bell, S
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2012

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