In vivo imaging of MMP-13 activity in the murine destabilised medial meniscus surgical model of osteoarthritis.
OBJECTIVE: To detect and determine disease severity of osteoarthritis (OA) using a probe activated by matrix metalloproteinase-13 (MMP-13) in vivo in the murine destabilised medial meniscus (DMM) surgical model of OA. DESIGN: We have previously described MMP12ap and MMP13ap, internally quenched fluo...
Hlavní autoři: | Lim, N, Meinjohanns, E, Meldal, M, Bou-Gharios, G, Nagase, H |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
Elsevier
2014
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