Stochastic detection of Pim protein kinases reveals electrostatically enhanced association of a peptide substrate.
In stochastic sensing, the association and dissociation of analyte molecules is observed as the modulation of an ionic current flowing through a single engineered protein pore, enabling the label-free determination of rate and equilibrium constants with respect to a specific binding site. We enginee...
Príomhchruthaitheoirí: | , , , , |
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Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
2013
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