Structures of SALSA/DMBT1 SRCR domains reveal the conserved ligand-binding mechanism of the ancient SRCR-fold

The scavenger receptor cysteine-rich (SRCR) family of proteins comprises more than 20 membrane-associated and secreted molecules. Characterised by the presence of one or more copies of the ∼110 amino-acid SRCR domain, this class of proteins have widespread functions as antimicrobial molecules, scave...

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Bibliographic Details
Main Authors: Reichhardt, M, Loimaranta, V, Lea, S, Johnson, S
Format: Journal article
Language:English
Published: Life Science Alliance 2020