Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin (AMVAC) as neoadjuvant chemotherapy for patients with muscle-invasive transitional cell carcinoma of the bladder.

BACKGROUND: Meta-analysis data demonstrate a 5% absolute survival benefit for neoadjuvant chemotherapy (NAC) using cisplatin-based combination regimens in the radical treatment of muscle-invasive bladder cancer (MIBC). However, there are no randomized, controlled trial data on the optimum regimen....

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Bibliographic Details
Main Authors: Blick, C, Hall, P, Pwint, T, Al-Terkait, F, Crew, J, Powles, T, Macaulay, V, Munro, N, Douglas, D, Kilbey, N, Protheroe, A, Chester, J
Format: Journal article
Language:English
Published: 2012