Interferon α-stimulated natural killer cells from patients with acute hepatitis C virus (HCV) infection recognize HCV-infected and uninfected hepatoma cells via DNAX accessory molecule-1.

BACKGROUND: Natural killer (NK) cells are an important component of the innate immune defense against viruses, including hepatitis C virus (HCV). The cell culture system using HCV-permissive Huh-7.5 cells make studies on interaction of NK cells and HCV-infected target cells possible. We used this s...

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Bibliographic Details
Main Authors: Stegmann, K, Björkström, N, Ciesek, S, Lunemann, S, Jaroszewicz, J, Wiegand, J, Malinski, P, Dustin, L, Rice, C, Manns, M, Pietschmann, T, Cornberg, M, Ljunggren, H, Wedemeyer, H
Format: Journal article
Language:English
Published: 2012