R-type Ca(2+)-channel-evoked CICR regulates glucose-induced somatostatin secretion.

Pancreatic islets have a central role in blood glucose homeostasis. In addition to insulin-producing beta-cells and glucagon-secreting alpha-cells, the islets contain somatostatin-releasing delta-cells. Somatostatin is a powerful inhibitor of insulin and glucagon secretion. It is normally secreted i...

Full description

Bibliographic Details
Main Authors: Zhang, Q, Bengtsson, M, Partridge, C, Salehi, A, Braun, M, Cox, R, Eliasson, L, Johnson, P, Renström, E, Schneider, T, Berggren, P, Göpel, S, Ashcroft, F, Rorsman, P
Format: Journal article
Language:English
Published: 2007